Goldcast Acquired by Cvent. Read more here!

Shake, Shake, Shake....

With stealth companies still developing there is plenty more to come in 2026!

AI robotics for industrial kitchens.
Making complex data flows observable, secure, and fixable.
Automated flow cytometry analysis and literature mapping.
AI-native reconciliation for fintechs.
AI-powered, prevention-led catastrophe insurance.
AI workflows for home services teams.
AI-enabled billing automation for PT clinics.
Capturing science’s unspoken know-how with AI.

Where These Relationships Begin

In 2025, the majority of new investments came from people who we’ve worked deeply with.

Some of these founders came to us through our Core Community. Even more came through portfolio company founders. Some through MIT dorm hallways, HBS classrooms, company alumni dinners, and one unforgettable conversation outside a Strava meetup.

Meet the Human-Stack
Behind Fund 3

Across the portfolio, we don’t just see sectors or stages. We see a pattern in the people: deep domain operators, AI-native technologists, go-to-market architects, mission-driven builders — often a blend all in one founding team.

We started thinking about them as layers in a Human-Stack.
  • They’ve lived the work. Former QSR Operators. CRE Brokers. Clinicians. Fintech Operators. Biotech Platform Leads. Construction Leaders. Restaurant Tech Operators.
  • They’ve built real systems, not just prototypes. Comp Bio PhDs. VP of Engineering at Thumbtack. Head of AI Engineering at Zapier. Robotics PhDs. API Engineering Lead at Strava.
  • They know how to get the product into the world. Klaviyo GTM Leaders. Substack Growth Engineers. Strava Partnerships Lead. Marketplace Builders. Community Architects. “Mafia Company” Spinouts.
  • They have the human attributes required to be successful. Gritty. High-Velocity Learner. Self-aware. Resilient. Deeply Motivated. Agile. Attractors. Authentic.
  • Who they are and how they show-up is their unfair advantage. Cave divers. Musicians. Caregivers. Teachers. Athletes. Advocates. Soldiers. Artisans. Parents.

Stories From the Portfolio: Flashbulb Memories from 2025


A kid’s first ride, powered by BusRight!
In a 20-second video, you see years of work pay off: safer routes, calmer parents, excited kids, and schools with real-time tracking. Behind every dashboard is a person whose day is better because the system works.


Hi Marley and Verisk team up to streamline property claims communication.
Claims are stressful by nature. This partnership brought clarity where there was chaos, helping insurers and homeowners communicate faster and with more empathy.

Slang launches its OpenTable partnership. From powering hospitality conversations to being spotlighted by OpenTable’s CEO and Fast Company, Slang crossed an important threshold this year: becoming essential to how restaurants connect with guests.

Quilt Partners with the National Alliance of Sickle Cell Centers. Together they’re creating a more effective, national, patient-centered ecosystem that speeds up the path to market for life-saving treatments. Talk about impact!

TetraScience launches its Scientific AI Lighthouse Program with Takeda. In 2025 TetraScience brought Scientific AI into action across life sciences R&D — advancing key collaborations with NVIDIA, Microsoft, Databricks, Snowflake, and other strategic partners.

CloudZero raises a $56M Series C and integrates with Anthropic. A defining year for the team: scaling the business, expanding the platform, and helping engineering and finance teams make better cloud decisions together.

Herald acquires AI-powered insurtech Babbix. By combining unified carrier connectivity with email-native AI, Herald advanced its mission to reshape broker workflows and modernize commercial insurance transactions.

We may measure progress in revenue, runway, and retention. But we remember it in these flashes — the human moments where something clicks.

    What we learned in 2025

    Enough with predictions. Here’s what actually changed us. Written in ink. Underlined in our notebooks. Lessons we’re taking into 2026.

    In an AI-saturated year, founders who deeply understand other humans — customers, teams, regulators, patients — stood out. EQ and AQ (adaptability quotient) were the real superpowers.

    - Lily Lyman

    The enduring power of real, offline relationships built by solving problems together over time. It’s how we’ve come to back over half the founders in our latest fund.

    - Brian Devaney

    It’s easy to be a good investor, CEO, or co-worker when things are rockin’, but relationships and reputations are built on how people show up when things are hard. There’s plenty of both in our business. Act accordingly!

    - Chris Gardner

    Venture works best when you get there before it all makes sense. The real outliers are built by tenacious founders in markets that still feel weird or uncertain — until they’re suddenly obvious to everyone else.

    - Richard Dulude

    Technology is advancing at a breathtaking pace; however, success still hinges on people. Founders who understand how humans adapt to new tools and how markets produce real outcomes are the ones building enduring companies.

    - James Orsillo

    Some of the most exciting relationships and ideas happen when we close the gap between Cambridge and downtown Boston, pairing incredible academic founders with experienced operators from the broader startup ecosystem.

    - Gabby McCarthy

    Thank You For Making 2025 So Memorable

    We don’t know exactly what 2026 will bring. But we know who we want to be there with — the founders, partners, and community members who made 2025 worth remembering.  

    A special thank you to our 2025 sponsors who make it all possible!

    Gold Sponsors
    Silver Sponsors